UP Comedy Club, Chicago
Second City's stand-up room in Piper's Alley, with headliners and showcases. 230 W North Ave, Chicago, IL. Lineups and tickets: https://www.upcomedyclub.com.
Clips filmed here
More clubs in Chicago
- The Second City: The sketch and improv theater that launched Bill Murray, Tina Fey, Stephen Colbert and Steve Carell.
- Zanies Chicago: Chicago's classic stand-up room in Old Town, intimate and brick-walled.
- Laugh Factory Chicago: Lakeview outpost of the Laugh Factory, with nightly showcases and touring headliners.
- The Lincoln Lodge: Chicago's long-running independent stand-up showcase, now in its own Logan Square home.
Updated November 12, 2026.